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Chicken Biscuit Casserole Recipe

Chicken Biscuit Casserole Recipe


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4.6 from 40 reviews

  • Total Time: 55 minutes
  • Yield: 8 1x

Description

Southern comfort meets creamy chicken bliss in this irresistible Chicken Biscuit Casserole. Layers of tender chicken, buttery biscuits, and rich sauce promise a hearty meal that warms hearts and satisfies hungry families with pure culinary comfort.


Ingredients

Scale

Protein:

  • 2 cups (473 ml) cooked chicken, shredded
  • 1 cup (240 ml) shredded cheddar cheese

Creamy Base:

  • 1 can (10.75 ounces/305 grams) cream of chicken soup
  • 1 cup (240 ml) sour cream
  • 1/2 cup (120 ml) milk
  • 1/2 teaspoon garlic powder
  • 1/4 teaspoon ground black pepper

Topping:

  • 1 can (16 ounces/454 grams) refrigerated biscuits
  • 1/2 cup (113 grams) butter, melted

Instructions

  1. Preheat the oven to 375°F and prepare a 9×13 inch baking dish with a light coating of cooking spray.
  2. In a spacious mixing bowl, thoroughly combine shredded chicken, cream soup, sour cream, shredded cheese, milk, garlic powder, and black pepper until ingredients are evenly distributed.
  3. Slice refrigerated biscuits into bite-sized quarters, then gently fold them into the creamy chicken mixture, ensuring each piece is lightly coated.
  4. Carefully spread the chicken and biscuit blend into the prepared baking dish, creating an even layer.
  5. Drizzle melted butter uniformly across the top of the casserole, which will help create a golden, crispy surface.
  6. Place the casserole in the preheated oven and bake for 35-40 minutes, watching for a rich golden-brown color and ensuring biscuits are fully cooked through.
  7. Remove from oven and let the casserole rest for 5-10 minutes before serving to allow the filling to set and cool slightly.

Notes

  • Customize protein by using rotisserie chicken, turkey, or even canned tuna for a quick swap.
  • Reduce sodium by choosing low-sodium cream soup and controlling added salt.
  • Add extra vegetables like diced bell peppers or frozen mixed vegetables for nutritional boost and color.
  • Make gluten-free by substituting regular biscuits with gluten-free biscuit mix and checking cream soup ingredients.
  • Prep Time: 15 minutes
  • Cook Time: 40 minutes
  • Category: Breakfast, Dinner, Snacks
  • Method: Baking
  • Cuisine: American

Nutrition

  • Serving Size: 8
  • Calories: 400
  • Sugar: 3g
  • Sodium: 950mg
  • Fat: 25g
  • Saturated Fat: 15g
  • Unsaturated Fat: 10g
  • Trans Fat: 0g
  • Carbohydrates: 30g
  • Fiber: 1g
  • Protein: 18g
  • Cholesterol: 80mg